Episode 103: Adverse drug reactions – how common are these in general practice and what are the implications for practice?

In this episode, we talk to Prof Emma Wallace, who is a GP and Professor of General Practice at University College Cork about the incidence and severity of adverse drug reactions in older adults in the community.

Title of paper: Cumulative incidence and severity of adverse drug reactions and associated patient characteristics in older community-dwelling adults attending general practice – a six year prospective cohort study

Available at:

No prospective studies have examined adverse drug reaction (ADR) occurrence among older adults attending general practice.  ADRs were found to occur for approximately 1 in 4 older adults over a six-year period.  Cardiovascular, nervous system and anti-infective drugs for systemic use were the most commonly implicated drug classes.  Approximately 1 in 4 ADRs rated as moderate result in additional healthcare utilisation.  Female sex, polypharmacy (5-9 drug classes) and major polypharmacy (≥10 drug classes) increased the likelihood for ADRs.

Previous Story

Ethics, COVID-19, and the common cold: Three examples of duties in tension with public health

Next Story

Ten things I wish I had known about academic primary care

Latest from Podcast

Skip to toolbar