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Episode 207: Risk of postural hypotension associated with antidepressants in older adults – what to think about when prescribing

 

Today, we’re speaking to Dr Cini Bhanu, GP and Academic Clinical Lecturer in the Primary Care and Population Health Department at University College London.

Title of paper: Antidepressants and risk of postural hypotension: a self-controlled case series study in UK primary care

Available at: https://doi.org/10.3399/BJGP.2024.0429

Antidepressants are associated with postural hypotension (PH). This is not widely recognised in general practice, where antihypertensives are considered the worst culprits. The present study examined >21 000 older adults and found a striking increased risk of PH with use of all antidepressants (over a four- fold risk with SSRIs) in the first 28 days of initiation.

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