Nigel Masters is a retired general medical practitioner. He summarises incoming medical notes. He has two active medical websites: https://www.smokingpackyears.com and https://www.clinicalindications.co.uk
We retired general medical practitioners strive to live long and well. The polypill1 might provide one part of this strategy. It is easy to take and as long as you have no side effects seems greatly beneficial. Of course, I was aware of the 2003 polypill paper in the British Medical Journal2 and have been on a cocktail of two antihypertension drugs at their lowest dose for over ten years. I have avoided aspirin which was in the original polypill as bleeding is a significant hazard. In addition, I do not tolerate statins due to troublesome gastrointestinal symptoms. My ‘white coat hypertension’ was discovered when I was being investigated for a blocked femoral artery in my left leg in my late fifties (cause unknown). This remains blocked and this in part explains why I need to exercise to keep my lower leg collateral blood vessels open.
So (apart from a Southern mediterranean diet) my main ‘health span’ extras are jogging and walking.
So (apart from a Southern mediterranean diet) my main ‘health span’ extras are jogging and walking. The Copenhagen City Heart Study3 suggests an extra 6.2 years of life at my age of seventy-one by doing at least two light jogs of half an hour duration. Think Tortoise rather than the Hare for running in older age. Here Parkrun is so useful as a motivator, and I have described this in the past.4 In addition, low dose exercise can prevent atrial fibrillation.5
Parkrun now has Park Walk version6 which can help people reach their daily step count. As little as 2400 steps daily can start reducing cardiovascular mortality and 4000 all-cause mortality (6). I attend a London walking group once midweek as part of my fitness regime and this occurs whatever the weather. Like Aesop’s Hare I do occasionally take a midday nap. I remain unconvinced that red wine is a healthy tipple but still partake. Inheriting good familial longevity genes could give one a head starts in the living long and well race, but I have a very mixed bag so running is my elixir of youth in an attempt to stretch those life limiting telomeres.
References
- Misselbrook D. A Secret Medicine BJGP Life 20th July 2024. https://bjgplife.com/a-secret-medicine/ [accesseed 13/9/24]
- Law MR, Wald NJ, Morris JK et al. Value of Low Dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials BMJ 2003;326:1427-31 doi: 10.1136/bmj.326.7404,1427pmid12829554
- Schnohr P, O’Keefe JH, Marott JL et al. Dose of jogging and long-term mortality: the Copenhagen City Heart Study J Am Coll Cardiol 2015 10;65(5):411-9. Doi: 10.1016/j.acc.2014.11.023
- Zacher J, Filipovic K, Predel G et al. Exercise and Atrial Fibrillation: the Dose makes the Poison? A Narrative Review. Int J Sports Med 2024 ;45(1) :17-22 doi :10.1055/a-2152-7628 pmid37802082
- Masters N. Parkrun eases the loneliness of the long-distance runner. Br J Gen Pract. 2014 Aug;64(625):408. doi: 10.3399/bjgp14X681025. PMID: 25071043; PMCID: PMC4111323.
- https://blog.parkrun.com/uk/2023/10/19/over-one-million-global-parkwalks/ [accessed 13/9/24]
- Banach M, Lewek J, Surma S et al. The association between daily step count and all-cause and cardiovascular mortality: a meta-analysis . European Journal of Preventative Cardiology 2023;30(18) :1975-85 https://doi.org/10.1093/eurjpc/zwad229
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